Methyl 2-amino-4,6-dichloropyridine-3-carboxylate
3-Pyridinecarboxylicacid, 2-amino-4,6-dichloro-, methyl ester
CAS: 1044872-40-3
Molecular Formula: C7H6Cl2N2O2
Methyl 2-amino-4,6-dichloropyridine-3-carboxylate - Names and Identifiers
Methyl 2-amino-4,6-dichloropyridine-3-carboxylate - Physico-chemical Properties
| Molecular Formula | C7H6Cl2N2O2 |
| Molar Mass | 221.04 |
| Density | 1.506 |
| Boling Point | 319.135 °C at 760 mmHg |
| Flash Point | 146.808 °C |
| Storage Condition | under inert gas (nitrogen or Argon) at 2–8 °C |
Methyl 2-amino-4,6-dichloropyridine-3-carboxylate - Introduction
Methyl 2-amino -4, 6-dichloronicotinate is an organic compound whose chemical formula is C7H6Cl2NO2. The following is a description of the properties, uses, preparation and safety information of the compound:
Nature:
-Appearance: 2-amino -4, 6-dichloronicotinic acid methyl ester is colorless or slightly yellow crystal.
-Solubility: It is soluble in some organic solvents such as ethanol and dichloromethane, but insoluble in water.
-Melting point: Its melting point is between 60-62°C.
Use:
-Drug intermediate: 2-amino -4, 6-dichloronicotinic acid methyl ester is an important intermediate for the synthesis of certain drugs, such as the synthesis of anti-rheumatic drugs.
Preparation Method:
- 2-amino -4, 6-dichloronicotinic acid methyl ester can be prepared by reacting 2,4-dichloronicotinic acid methyl ester with ammonia. The reaction is generally carried out under suitable reaction conditions, such as in an organic solvent, at room temperature or at low temperature.
-reaction equation: 2,4-dichloronicotinic acid methyl ester NH3 -> 2-amino -4,6-dichloronicotinic acid methyl ester HCl
Safety Information:
- 2-amino -4, 6-dichloronicotinic acid methyl ester is an organic compound that may cause irritation and damage to the human body when exposed. Therefore, it is necessary to take appropriate protective measures during use and operation, such as wearing protective gloves and glasses, and operating in a well-ventilated environment.
-When storing, it should be stored in a dry, cool place, and away from fire and oxidants.
-When disposing of waste, local environmental laws and regulations need to be observed.
Nature:
-Appearance: 2-amino -4, 6-dichloronicotinic acid methyl ester is colorless or slightly yellow crystal.
-Solubility: It is soluble in some organic solvents such as ethanol and dichloromethane, but insoluble in water.
-Melting point: Its melting point is between 60-62°C.
Use:
-Drug intermediate: 2-amino -4, 6-dichloronicotinic acid methyl ester is an important intermediate for the synthesis of certain drugs, such as the synthesis of anti-rheumatic drugs.
Preparation Method:
- 2-amino -4, 6-dichloronicotinic acid methyl ester can be prepared by reacting 2,4-dichloronicotinic acid methyl ester with ammonia. The reaction is generally carried out under suitable reaction conditions, such as in an organic solvent, at room temperature or at low temperature.
-reaction equation: 2,4-dichloronicotinic acid methyl ester NH3 -> 2-amino -4,6-dichloronicotinic acid methyl ester HCl
Safety Information:
- 2-amino -4, 6-dichloronicotinic acid methyl ester is an organic compound that may cause irritation and damage to the human body when exposed. Therefore, it is necessary to take appropriate protective measures during use and operation, such as wearing protective gloves and glasses, and operating in a well-ventilated environment.
-When storing, it should be stored in a dry, cool place, and away from fire and oxidants.
-When disposing of waste, local environmental laws and regulations need to be observed.
Last Update：2024-04-09 20:48:19
